Updated on 2024/06/06

写真a

 
OKUDA Kenichi
 
Organization
Faculty of Engineering Department of Life, Environment and Applied Chemistry Associate Professor
Graduate School of Engineering Master's program Life, Environment and Applied Chemistry Associate Professor
Title
Associate Professor
Contact information
メールアドレス
External link

Degree

  • 博士(農学) ( 2008.3   九州大学 )

Research Interests

  • Antibiotic resistance

  • MRSA

  • Staphylococcus aureus

  • Propionibacterium acnes

  • Biofilm

  • Bacteriocin

  • 化合物スクリーニング

  • Infection

  • Bacteria

Research Areas

  • Life Science / Bacteriology  / Bacteriology

  • Life Science / Applied microbiology

  • Life Science / Pharmaceutical chemistry and drug development sciences  / ケミカルバイオロジー

Education

  • Kyushu University

Research History

  • Fukuoka Institute of Technology   Faculty of Engineering Department of Life, Environment and Materials Science   Associate Professor

    2023.4

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  • Jikei University   Lecturer

    2015.4 - 2023.3

  • Jikei University   Assistant Professor

    2011.10 - 2015.3

  • 理化学研究所   生命分子システム基盤研究領域   研究員

    2009.2 - 2011.9

  • Kyushu University   Special researcher of the Japan Society for the Promotion of Science

    2008.4 - 2009.1

Professional Memberships

  • THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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  • THE JAPANESE SOCIETY FOR BIOFILM RESEARCH

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  • 日本細菌学会

  • 日本化学療法学会

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Committee Memberships

  • 日本バイオフィルム学会   広報委員  

    2017.8   

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  • 日本バイオフィルム学会   評議員  

    2015.8   

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    Committee type:Academic society

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Papers

  • Effects of bacteriocins on methicillin-resistant Staphylococcus aureus biofilm Reviewed

    Ken-ichi Okuda, Takeshi Zendo, Shinya Sugimoto, Tadayuki Iwase, Akiko Tajima, Satomi Yamada, Kenji Sonomoto, Yoshimitsu Mizunoe

    Antimicrobial Agents and Chemotherapy   2013.11

  • Norgestimate inhibits staphylococcal biofilm formation and resensitizes methicillin-resistant Staphylococcus aureus to β-lactam antibiotics Reviewed

    Yutaka Yoshii, Ken-ichi Okuda, Satomi Yamada, Mari Nagakura, Shinya Sugimoto, Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Takeo Iwamoto, Kazuyoshi Kuwano, Yoshimitsu Mizunoe

    NPJ biofilms and microbiomes   2017.7

  • The composition and structure of biofilms developed by Propionibacterium acnes isolated from cardiac pacemaker devices Reviewed

    Ken-ichi Okuda, Ryuichi Nagahori, Satomi Yamada, Shinya Sugimoto, Chikara Sato, Mari Sato, Tadayuki Iwase, Kazuhiro Hashimoto, Yoshimitsu Mizunoe

    Frontiers in Microbiology   2018.2

  • Roles of lytic transglycosylases in biofilm formation and β-lactam resistance in methicillin-resistant Staphylococcus aureus Reviewed

    Anne-Aurelie Lopes, Yutaka Yoshii, Satomi Yamada, Mari Nagakura, Yuki Kinjo, Yoshimitsu Mizunoe, Ken-ichi Okuda

    Antimicrobial agents and chemotherapy   2019.9

  • Small-Molecule-Induced Activation of Cellular Respiration Inhibits Biofilm Formation and Triggers Metabolic Remodeling in Staphylococcus aureus Reviewed

    Ken-ichi Okuda, Satomi Yamada-Ueno, Yutaka Yoshii, Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Yoshimitsu Mizunoe, Yuki Kinjo

    mBio   2022.7

  • Common Features and Intra-Species Variation of Cutibacterium modestum Strains, and Emended Description of the Species Reviewed

    Itaru Dekio, Ken-Ichi Okuda, Masako Nishida, Susumu Hamada-Tsutsumi, Tomo Suzuki, Shigeru Kinoshita, Hiroto Tamura, Kenichiro Ohnuma, Yoshiyuki Murakami, Yuki Kinjo, Akihiko Asahina

    Microorganisms   2021.11

  • Detection of bacterial DNA from central venous catheter removed from patients by next generation sequencing: a preliminary clinical study Reviewed

    Ken-ichi Okuda, Yutaka Yoshii, Satomi Yamada, Akio Chiba, Ippei Hironaka, Seiji Hori, Katsuhiko Yanaga, Yoshimitsu Mizunoe

    Annals of Clinical Microbiology and Antimicrobials   2018.12

  • Imaging of bacterial multicellular behaviour in biofilms in liquid by atmospheric scanning electron microscopy Reviewed

    Shinya Sugimoto, Ken-ichi Okuda, Reina Miyakawa, Mari Sato, Ken-ichi Arita-Morioka, Akio Chiba, Kunitoshi Yamanaka, Teru Ogura, Yoshimitsu Mizunoe, Chikara Sato

    Scientific Reports   2016.5

  • Immuno-Electron Microscopy of Primary Cell Cultures from Genetically Modified Animals in Liquid by Atmospheric Scanning Electron Microscopy Reviewed

    Takaaki Kinoshita, Yosio Mori, Kazumi Hirano, Shinya Sugimoto, Ken-ichi Okuda, Shunsuke Matsumoto, Takeshi Namiki, Tatsuhiko Ebihara, Masaaki Kawata, Hidetoshi Nishiyama, Mari Sato, Mitsuo Suga, Kenichi Higashiyama, Kenji Sonomoto, Yoshimitsu Mizunoe, Shoko Nishihara, Chikara Sato

    Microscopy and Microanalysis   2014.4

  • A Simple Assay for Measuring Catalase Activity: A Visual Approach Reviewed

    Tadayuki Iwase, Akiko Tajima, Shinya Sugimoto, Ken-ichi Okuda, Ippei Hironaka, Yuko Kamata, Koji Takada, Yoshimitsu Mizunoe

    Scientific Reports   2013.11

  • Staphylococcus epidermidis Esp degrades specific proteins associated with Staphylococcus aureus biofilm formation and host-pathogen interaction Reviewed

    (Shinya Sugimoto, Takeo Iwamoto, Koji Takada, Ken-ichi Okuda, Akiko Tajima, Tadayuki Iwase, Yoshimitsu Mizunoe

    Journal of Bacteriology   2013.10

  • Glucose triggers ATP secretion from bacteria in a growth-phase-dependent manner Reviewed

    Ippei Hironaka, Tadayuki Iwase, Shinya Sugimoto, Ken-ichi Okuda, Akiko Tajima, Katsuhiko Yanaga, Yoshimitsu Mizunoe

    Applied and Environmental Microbiology   2013.4

  • Structural basis for extracellular interactions between calcitonin receptor-like receptor and receptor activity-modifying protein 2 for adrenomedullin-specific binding Reviewed

    Seisuke Kusano, Mutsuko Kukimoto-Niino, Nobumasa Hino, Noboru Ohsawa, Ken-ichi Okuda, Kensaku Sakamoto, Mikako Shirouzu, Takayuki Shindo, Shigeyuki Yokoyama

    Protein Science   2012.2

  • Enhanced production of nukacin D13E in Lactococcus lactis NZ9000 by the additional expression of immunity genes Reviewed

    Tijo Varghese Puramattathu, Mohammad R Islam, Mami Nishie, Sae Yanagihara, Jun-ichi Nagao, Ken-ichi Okuda, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

    Applied Microbiology and Biotechnology   2012.1

  • Structural and functional diversity of lantibiotic immunity proteins Reviewed

    en-ichi Okuda, Kenji Sonomoto

    Current Pharmaceutical Biotechnology   2011.8

  • Functional significance of the E Loop, a novel motif conserved in the lantibiotic immunity ATP-binding cassette transport systems Reviewed

    Ken-ichi Okuda, Sae Yanagihara, Tomomichi Sugayama, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

    Journal of Bacteriology   2010.6

  • Binding specificity of the lantibiotic-binding immunity protein NukH Reviewed

    Ken-ichi Okuda, Sae Yanagihara, Kouki Shioya, Yoshitaka Harada, Jun-ichi Nagao, Yuji Aso, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

    Applied and Environmental Microbiology   2008.12

  • Identification of the nukacin KQU-131, a new type-A(II) lantibiotic produced by Staphylococcus hominis KQU-131 isolated from Thai fermented fish product (Pla-ra) Reviewed

    Pongtep Wilaipun, Takeshi Zendo, Ken-ichi Okuda, Jiro Nakayama, Kenji Sonomoto

    Bioscience Biotechnology Biochemistry   2008.8

  • Cooperative transport between NukFEG and NAH in immunity against the lantibiotic nukacin ISK-1 produced by Staphylococcus warneri ISK-1 Reviewed

    Ken-ichi Okuda, Yuji Aso, Jiro Nakayama, Kenji Sonomoto

    Journal of Bacteriology   2008.1

  • Lantibiotics: Insight and foresight for new paradigm Reviewed

    Jun-ichi Nagao, Sikder M. Asaduzzaman, Yuji Aso, Ken-ichi Okuda, Jiro Nakayama, Kenji Sonomoto

    Journal of Bioscience and Bioengineering   2006.9

  • Characterization of functional domains of lantibiotic-binding immunity protein, NukH, from Staphylococcus warneri ISK-1 Reviewed

    Ken-ichi Okuda, Yuji Aso, Jun-ichi Nagao, Kouki Shioya, Youhei Kanemasa, Jiro Nakayama, Kenji Sonomoto

    FEMS Microbiology Letters   2005.9

  • A novel type of immunity protein, NukH, for the lantibiotic nukacin ISK-1 produced by Staphylococcus warneri ISK-1 Reviewed

    Yuji Aso, Ken-ichi Okuda, Jun-ichi Nagao, Youhei Kanemasa, Nguyen Thi Bich Phuong, Hanako Koga, Kouki Shioya, Toshihiro Sashihara, Jiro Nakayama, Kenji Sonomoto

    Bioscience Biotechnology Biochemistry   2005.7

  • Heterologous expression and functional analysis of the gene cluster for the biosynthesis of and immunity to the lantibiotic, nukacin ISK-1 Reviewed

    (Yuji Aso, Jun-ichi Nagao, Hanako Koga, Ken-ichi Okuda, Youhei Kanemasa, Toshihiro Sashihara, Jiro Nakayama, Kenji Sonomoto

    Journal of Bioscience and Bioengineering   2004.12

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Books

  • 黄色ブドウ球菌バイオフィルム形成阻害剤のスクリーニングと作用機序の解析

    奥田 賢一

    バイオフィルム 革新的制御技術  2023.6 

  • 4-28 鼻咽腔と咽頭の微生物

    吉井 悠、奥田 賢一、杉本 真也

    食と微生物の事典  2017.6 

  • 病原体別感染症編

    水之江 義充、岩瀬忠行、杉本 真也、奥田 賢一、千葉 明生

    感染症症候群(第2版)上  2013.7 

  • Engineering unusual amino acids into peptides using lantibiotic synthetase

    Jun-ichi Nagao, Kouki Shioya, Yoshitaka Harada, Ken-ichi Okuda, Takeshi Zendo, Jiro Nakayama, Kenji Sonomoto

    Methods in Molecular Biology  2011.10 

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    Language:English  

Industrial property rights

  • バイオフィルム形成抑制剤

    奥田 賢一

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    Application no:特願2021-196755 

Research Projects

  • バイオフィルム形成機構に立脚した阻害法の開発

    2014

    科研費  基盤研究(B)

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    Authorship:Coinvestigator(s)  Grant type:Competitive

    Grant amount:\16200000

  • 創薬を指向した新規バイオフィルム形成阻害物質の作用機序研究

    2014

    科研費  若手研究(B)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3900000

Teaching Experience (On-campus)

  • 2023   Experiments of Chemistry

  • 2023   Introduction to Life, Environment and Applied Chemistry

  • 2023   Applied Microbiology

  • 2023   Seminar Ⅰ for life environment and

  • 2023   Seminar Ⅱ for life environment and

  • 2023   Graduation Study

  • 2023   Advanced Applied Microbiology

  • 2023   Advanced Environmental Bioscience I

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Teaching Experience

  • 化学実験

    2023.9 Institution:福岡工業大学

  • 応用微生物学特論

    2023.9 Institution:福岡工業大学

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    Level:Postgraduate 

  • 応用微生物学

    2023.4 Institution:福岡工業大学

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    Level:Undergraduate (specialized) 

  • 環境生物科学特論I

    2023.4 Institution:福岡工業大学

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    Level:Postgraduate